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Cat. No. | Product Name | ||
---|---|---|---|
L4100 | TGF-β/Smad靶点化合物库 | 184 compounds | |
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75005 |
TGFβ1-IN-3
|
Others | Others |
TGFβ1-IN-3 是一种二芳基酰基腙衍生物,对成纤维细胞的活化和增殖有抑制作用。TGFβ1-IN-3 是治疗特发性肺纤维化 (IPF) 的候选化合物。 | |||
T9523 |
TGFβRI-IN-3
|
TGF-beta/Smad | Stem Cells |
TGFβRI-IN-3 抑制TGFβR1,IC50为 0.79 nM,是对 MAP4K4 的选择性2000 倍。TGFβRI-IN-3 是一种高选择性的 TGFβR1 抑制剂,在免疫肿瘤中具有潜在的应用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06247 |
TGF beta 3 Protein, Human, Recombinant (hFc)
TGF-beta 3,ARVD,TGF β3,TGF |
Human | HEK293 Cells |
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is P10600-1. | |||
TMPK-00258 |
Latent TGF beta 3 Protein, Human, Recombinant (His)
TGFβ3,转化生长因子,TGF-β3,... |
Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 45.9 kDa and t... | |||
TMPK-00259 |
Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TGF-beta3,TGFβ,TGF-β,TGF... |
Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predi... | |||
TMPJ-00255 |
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
ARVD,TGF-β3,TGFB3,转化生长因子,TGF<... |
Human | HEK293 Cells |
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600. | |||
TMPJ-00256 |
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
Transforming growth factor β-3,Latent TGF-β3 |
Human | HEK293 Cells |
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600. | |||
TMPJ-00254 |
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
Latency-associated peptide,TGF-beta-3,Transforming ... |
Human,Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regu... | |||
TMPJ-00771 |
TGF beta 1 Protein, Mouse/Rat, Recombinant
TGFB,TGFbeta,CEDLAP,TGF-beta-1, |
Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)... |